BDBM25761 Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine

SMILES CC(C)NCC(O)COc1cccc2ccccc12

InChI Key InChIKey=AQHHHDLHHXJYJD-UHFFFAOYSA-N

Data  81 KI  59 IC50  34 Kd  26 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25761   

TargetMu-type opioid receptor(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM25761(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Affinity DataIC50: <5.01E+3nMAssay Description:Antagonist activity at human wild-type opioid-mu receptor expressed in CHO-K1 cells assessed as DAMGO-induced cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM25761(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Affinity DataEC50: <5.01E+3nMAssay Description:Agonist activity at human wild-type opioid-mu receptor expressed in CHO-K1 cells assessed as cAMP level by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed